Hi, I was told a week ago that I have pre cancerous cells in my right breast and need to have a mastectomy. Right now, I'm wondering if having pre cancerous cells in one part of the body means there may be more elsewhere? I'm struggling to believe that I'll simply have the breast removed and reconstructed and that's that if you know what I mean? Although the word pre cancer is the wrong definition of what we have as there is no guarantee that these cells will become cancerous. What grade are the cells?
Metrics details. The presence of disseminated tumor cells DTCs in bone marrow BM is an independent prognostic factor in early breast cancer but does not uniformly predict outcome. Tumor cells can persist in a quiescent state over time, but clinical studies of markers predicting the awakening potential of DTCs are lacking. Samples collected at two or more time points were available for 24 patients. Fifteen samples were also analyzed for the proliferation marker Ki Our study translates findings from basic biological analysis of DTC dormancy to the clinical situation and supports further clinical studies of NR2F1 as a marker of dormancy. Breast cancer patients may experience relapse and subsequent death from the disease many years after primary treatment.
Sylvie Tremblay holds a Master of Science in molecular and cellular biology and has years of experience as a cancer researcher and neuroscientist. Breast cells undergo cycles of proliferation and maturation throughout the menstrual cycle and during pregnancy. These cycles of cell growth are governed by a number of molecular signals that guide the behavior of the cells. When breast cells develop genetic mutations, they begin to proliferate regardless of external signaling and begin to form of a tumor.
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