Breast Cancer Research and Treatment. Primary and secondary breast angiosarcoma is a rare and aggressive malignancy with limited published literature. Optimal management is mostly based on expert opinion. Our study aims to describe a single institution experience with breast angiosarcoma and evaluate other publications on this topic to further clarify prognostic outcomes and treatment modalities in this disease. Twenty two cases of breast angiosarcoma from Roswell Park Comprehensive Cancer Center were retrospectively analyzed. Additionally, a systemic review and meta-analysis was conducted to study the association between survival outcomes, overall survival OS , and recurrence-free survival RFS in both primary PAS and secondary breast angiosarcoma SAS.
Radiation induced angiosarcoma RIAS of the breast is a rare and aggressive complication of radiotherapy. Due to the rarity of this disease, much of the evidence for its management is based on case reports or small retrospective series. We sought to describe the management and outcomes of RIAS in a large single-institution series. All patients diagnosed with RIAS between January and January were identified from an institutional database. A total of 49 patients were identified. Median time from completion of radiotherapy to diagnosis of RIAS was 7.
I just want to let you know that I have decided to create a newer version of this page with more up-to-date information on Angiosarcoma of the Breast. An angiosarcoma could therefore develop in virtually any area of the body, but a breast angiosarcoma usually starts in the cells which line the blood vessels of the breast or the underarm area. In terms of breast cancers, angiosarcomas account for a very small percentage of cases; less than 0. Breast angiosarcomas are also sometimes referred to by different names, such as mammary angiosarcoma, hemangiosarcoma of the breast, and lymphangiosarcoma if it develops in the area of the lymph nodes. Once they develop, an angiosarcoma of the breast tends to grow and spread rather quickly.
Angiosarcoma of the breast is an uncommon type of breast cancer that begins in the blood or lymphatic vessels within the breast and tends to be aggressive and spread rapidly. Accounting for only around 0. Primary angiosarcomas have no known risk factors, and often develop in young women. Secondary angiosarcomas , which are less common, arise after a woman has had radiation therapy to the breast for a different breast cancer.
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